![The cholesterol uptake regulator PCSK9 promotes and is a therapeutic target in APC/KRAS-mutant colorectal cancer | Nature Communications The cholesterol uptake regulator PCSK9 promotes and is a therapeutic target in APC/KRAS-mutant colorectal cancer | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-022-31663-z/MediaObjects/41467_2022_31663_Fig1_HTML.png)
The cholesterol uptake regulator PCSK9 promotes and is a therapeutic target in APC/KRAS-mutant colorectal cancer | Nature Communications
![Frontiers | Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation Frontiers | Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation](https://www.frontiersin.org/files/Articles/687515/fcell-09-687515-HTML/image_m/fcell-09-687515-g001.jpg)
Frontiers | Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation
![Evolving synergistic combinations of targeted immunotherapies to combat cancer | Nature Reviews Cancer Evolving synergistic combinations of targeted immunotherapies to combat cancer | Nature Reviews Cancer](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fnrc3973/MediaObjects/41568_2015_Article_BFnrc3973_Fig1_HTML.jpg)
Evolving synergistic combinations of targeted immunotherapies to combat cancer | Nature Reviews Cancer
![Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming | Nature Structural & Molecular Biology Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming | Nature Structural & Molecular Biology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41594-020-0424-6/MediaObjects/41594_2020_424_Fig1_HTML.png)
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming | Nature Structural & Molecular Biology
![Spatiotemporal regulation of the anaphase-promoting complex in mitosis | Nature Reviews Molecular Cell Biology Spatiotemporal regulation of the anaphase-promoting complex in mitosis | Nature Reviews Molecular Cell Biology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnrm3934/MediaObjects/41580_2015_Article_BFnrm3934_Fig1_HTML.jpg)
Spatiotemporal regulation of the anaphase-promoting complex in mitosis | Nature Reviews Molecular Cell Biology
![Cancers | Free Full-Text | Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q Cancers | Free Full-Text | Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q](https://pub.mdpi-res.com/cancers/cancers-13-05084/article_deploy/html/images/cancers-13-05084-g001-550.jpg?1634641716)
Cancers | Free Full-Text | Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q
![Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis | Oncogene Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis | Oncogene](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fonc.2012.486/MediaObjects/41388_2013_Article_BFonc2012486_Fig1_HTML.jpg)
Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis | Oncogene
![Frontiers | Immunomodulation in Administration of rAAV: Preclinical and Clinical Adjuvant Pharmacotherapies Frontiers | Immunomodulation in Administration of rAAV: Preclinical and Clinical Adjuvant Pharmacotherapies](https://www.frontiersin.org/files/Articles/658038/fimmu-12-658038-HTML/image_m/fimmu-12-658038-g001.jpg)